Discuss the practical or clinical significance of the findings to the evidence­based practice of nursing.

Risk of Developing Venous Thromboembolism in I

The name of my research project is Risk of Developing Venous Thromboembolism in Immobilized

Patients.

My PICO question for the project is

PICO question: In immobilized patient who is at risk for developing venous thromboembolism, how

does pharmacological prophylaxis (antiplatelet agents) compared to mechanical prophylaxis

(intermittent compression devices) affect the development of venous thromboembolism within 1

week of treatment?

You have to choose any 4 article from the list provided below:

­ Frontera, J. A., Jovine, M., Hunter, S., Catalano, A., & Gordon, E. (2014). Comparison of

Pharmacologic versus Mechanical Venous Thromboemoblism Prophylaxis in Patients with Intracranial

Hemorrhage. Stroke, 45(Supp.1).

­ Gaspard, D., Vito, K., Gerber, D. (2015). Comparison of Chemical and Mechanical Prophylaxis of

Venous Thromboembolism in Nonsurgical Mechanically Ventilated Patients. Thrombosis, 2015: 1 – 6.

­ Gharabaghi, M. & Meshkini, A. (2015). A Comparison of pharmacologic and mechanical prophylaxis

on the prevention of deep vein thrombosis in spinal cord injury. Trauma monthly, 20(Special Issue):

e28508.

­ Holwell, A., McKenzia, J., Holmes, M., Woods, R., Nandurkar, H., Tam, C. S., & Bazargan, A.

(2014). Venous thromboembolism prevention in patients undergoing colorectal surgery for cancer.

ANZ Journal of Surgery, 84, 284­288.

­ Phillips, N. M. & Heazlewood, V. J. (2012). Venous thromboembolism prophylaxis audit in two

Queensland hospitals. International Medicine Journal, 43(5), 560­6. Doi: 10.1111/imj.12033.

­ Pontelli, E., Scialom, J., Dos, T. & Pontelli2, S. (2012). Pharmacologic and intermittent pneumatic

compression thromboembolic prophylaxis in 563 consecutive abdominoplasty cases. Revista Brasileira

de Cirurgia Plástica, 27(1): 77 – 86.

­ Sobieraj­Teague, S., Hirsh, J., Yip, G……..Eikelboom, J. (2012). Randomized controlled trial of a

new portable calf compression device (Venowave) for prevention of venous thrombosis in high­risk

neurosurgical patients. Journal of Thrombosis and Haemostasis, 10(2): 229 – 235.

­ Yamamoto, T., Nakamura, M., Kuroiwa, M., & Tanaka, K. (2013). Current prevention practices for

venous thromboembolism in Japanese intensive care units. Journal of Anesthesia, 27, 931­934. Doi:

10.1007/s00540­013­1626­4.

1. Describe similarities in research methods across the four studies

2. Describe differences in research methods across the four studies.

3. Discuss the practical or clinical significance of the findings to the evidence­based practice of

nursing.

4. Provide an answer to the PICO question, or describe why you are not able to definitively answer

the question.

5. References should include 4 articles you have picked and 1 more additional reference you allowed

if you need to use to describe similarities and differences of research methods. (number of sources 4­