Why this drug important

1- 5-fluorouracil (5-FU) introduction 2- Why this drug important 3- 5-FU inhibition and colorectal cancer 4- Use this drug (5 -FU) as combination drugs Doxorubicin or celecoxib 5- Recent research studies about used as 5-FU a good drug in chemotherapy 6- i need between 15 to 20 references and must be each sentence conform with reference ( in text reference )please and please used Harved style . Also, important used some update journal from 2017 to 2019 .

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